Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWTGATITVKIKCPEESASHLHV-KNA-TMGYL-------TSSLSTKL-IPAIYLLVFVVGVPANAVTLWMLFFRTR-SICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLA-----FFGFLIPFVLIIYCYAAIIRTL---------NAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYL-IALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK 4N6H Chain:A ((88-399)) ------------------------------------------------------------------KVKEAQAAAEQLKTTRNAYIQKYLGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLM-ETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMA---------VTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTL-VDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCR

General information: TITO was launched using: RESULT: Template: 4N6H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -278910 for 2057 contacts (-135.6/contact) + 2D Compatibility (PS) -29134 + (NN) -7288 + (LL) 4400 1D Compatibility (HY) -24400 + (ID) 4300 Total energy: -339632.0 ( -165.11 by residue) QMean score : 0.220

(partial model without unconserved sides chains): PDB file : Tito_4N6H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4N6H-query.scw PDB file : Tito_Scwrl_4N6H.pdb: