Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKVRKSFVLLLTGLLAVLILSACGQKTQQDIVAGLDEKAKEYTSYKAKAKMTIETGSE--PQVYNVEIW-H--KKPS-LYRVYLENPKKDQNQVIL-------RNENGVFVLTPSLNKSFRFQSDWPN-NS-SQVYLFESLVKD-VQNDSDAVFTAK-----EKKYVFETKTNY-QHNKMLPTQEITFNKKDMSPSSVKVMDTDRK------------------------------VMVKVEFSSFEFNKQFDKESFDEKKNMTLSQMDVATSAKPSDTFAVKTPLELPLGVKLLEEKDISTEDGKRIIMTYGGEKSFTLIQEKAQIAKASSSVTLNGEPVNLGYTIGALSDASLSWTYDGVDYLLSSKDLSKEEMVTVAKSMQGQSSK 4Z48 Chain:A ((10-242)) --------------------------KAGYDLAVRMDQVDTS-QDSYSEAVMSINRGGKVLTRSFKTYSKHFGKDGKDEYSLIVFDRPADVNGTKYLVWSYRGLEQDDDMWVYLPAESLVRRISGSSKFASFMRSDLSNEDIQNLDDVDEYDYLLQGEENVDGIDCYILERTPKKGKE-TQYSRQVQWVRKDTLLRLRADYYDKKDRLVKKLFFSRQEKIDGIWTVTQMRVERPREGSFTVIDWSNLRYDVGLSDAYFEHS---------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4Z48.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 729 -20804 -28.54 -114.94 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : -28.54 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.443

(partial model without unconserved sides chains): PDB file : Tito_4Z48.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Z48-query.scw PDB file : Tito_Scwrl_4Z48.pdb: