Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDVRNKTLWILRDYVYILIGAAITAVSFNVFLLPNKIAAGGVSGISTILQSYGFEAAYVQWIINIPLFIAGVILLGGKFGLKTLAGSVFLPLVVFLTRDIQPATHHELLAAIFGGVGIGIGIGIVYLGKGSTGGTALAAQIIHKYSGLSLGKCLAIIDGMIVVTAMIVFNIEQGLYAMLGVYVSSKTIDVVQVGFNRSKMALIITKQ--EQAVKEAVLQKIDRGVTKISAVGGYTD---------------DDRPI-LMCVVGQTEFTKLKQIVKQIDE-----SAFVIVADASEVLGEGFKRA 1VFJ Chain:A ((4-101)) --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IVAIVRPEKLNEVLKALFQAEVRGLTLSRVQGHGGETERVETYRGTTVKMELHEKVRLEIGVSEPFVKPTVEAILKAARTGEVGDGKIFVLPVEKVYR------

General information: TITO was launched using: RESULT: Template: 1VFJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 225 2812 12.50 37.49 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.46 3D Compatibility (PKB) : 12.50 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.46 QMean score : 0.418

(partial model without unconserved sides chains): PDB file : Tito_1VFJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VFJ-query.scw PDB file : Tito_Scwrl_1VFJ.pdb: