Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVR-HAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF--FTAPLPAHPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 2WIP Chain:A ((6-299)) MENFQKVEKIG-----VVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKEL-NHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY-KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2WIP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -197404 for 2278 contacts (-86.7/contact) + 2D Compatibility (PS) -29860 + (NN) -15203 + (LL) 1132 1D Compatibility (HY) -32000 + (ID) 6350 Total energy: -279685.0 ( -122.78 by residue) QMean score : 0.521

(partial model without unconserved sides chains): PDB file : Tito_2WIP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2WIP-query.scw PDB file : Tito_Scwrl_2WIP.pdb: