Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIE--DNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRR-VMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTASS 2XKE Chain:A ((7-262)) --------------------------------DYEVLYTIGTG---RCQKIRRKSDGKILVWKELDYGSMTEAEKQM-LVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHRRSD-----LKPANVFLDGKQNVKLGDF------------------TPYYMSPEQMN----NEKSDIWSLGCLLYELCALMPPFTA--FSQKELAGKIREGKFRRIPY-RYSDELNEIITRMLNLKDYHRPSVEEILENPLILEHHHHHH

General information: TITO was launched using: RESULT: Template: 2XKE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -137130 for 1582 contacts (-86.7/contact) + 2D Compatibility (PS) -23855 + (NN) -16674 + (LL) 2524 1D Compatibility (HY) -21200 + (ID) 4150 Total energy: -200485.0 ( -126.73 by residue) QMean score : 0.565

(partial model without unconserved sides chains): PDB file : Tito_2XKE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XKE-query.scw PDB file : Tito_Scwrl_2XKE.pdb: