Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLHVAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLDCLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRDPKLYAMH--PWVTSKPLPEY-------LWKKIANNCIFIVIHRSTTSQ--TIKVSPDDTPGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNGEEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRKFRVK-IRGIDIPVLPRNTDLTV--FVEANIQHGQQVLCQRRTSPK-PFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILL-DNYCHPIALPKHQPTPDPEGDRVRAEMPN--QLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKH-PKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQK----VTLDIKSLSAEKYDVSSQVI---SQLKQKLENLQNSQLPESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQ--QSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA 2Y3A Chain:A ((141-1085)) --------------------------------------------------------------------------------------------------------------------------------------------------AEKLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEAKIQS----LVGLSWIDWLKHTYPPEHEPSVLENLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINE---LAIQKRLT-------ASPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECC--KIKKMYEQEMIAIEAAI-----------------------IWDNNNPFQITLVKGNKL-----NTEETVKVHVRAGLFHGTELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAV------------------------VAWVNTMVFDFKGQLRSGDVILHSWS-SFPDELEEMLNPMG-TVQTNPYAENATALHITFPENKKQPCYYPPFDKIIEKAAELA------GKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVA---QLQALLQIWPK--LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALDNRRIGQFLFWHLRSEV-HTPAVSVQFGVILEAYCRG-SVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLSRAKGKEAMHTCLKQSAYREALSDLQS---------PLNPCVILSELYVEKCKYMDSKMKPLWLVYSS---RAFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDD-LDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHT------------

General information: TITO was launched using: RESULT: Template: 2Y3A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -474398 for 6760 contacts (-70.2/contact) + 2D Compatibility (PS) -90934 + (NN) -32525 + (LL) 16888 1D Compatibility (HY) -76800 + (ID) 16550 Total energy: -674319.0 ( -99.75 by residue) QMean score : 0.427

(partial model without unconserved sides chains): PDB file : Tito_2Y3A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Y3A-query.scw PDB file : Tito_Scwrl_2Y3A.pdb: