Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQEKRLKAIQNKIASWIKEIESGFIDALFSKIGP--SKMLRSKLMLALLDEKTDAI-LLDKALNLCAIVEMIQTASLLHDDVIDKATMRRKLPSINALFGNFNAVMLGDVFYSKAFFELSKMGES-IAQALSNAVLRLSRGE-IEDVFVGECFNSDKQKYWRILEDKTAHFIEASLKSMAILLNKDAKMYADFGLHFGMAFQIIDDLLDITQDANTLGKPNFSDFKEGKTTLPYLLLYEKLNQHEQGLLISYFKQDSHEIIEWTKEKFKQHGII---EETLKIAQVYSKKALEAIKGENNLILEKLAQDVIYRTF 1V4I Chain:A ((15-273)) -----------KVKERIEQILSQFFPEQIMKDLPLYGKMLRVRL--SILSFKNRGVEIGEDAISSLAALELVHLASLLHDDVIDGARFRRGKETINFMYGDKAAVAAGDLVLVSAFHTVEEIGNNKLRRAALNVIGKMSEAELIEQLSRYKPIT--KEEYLRIVEGKSGALFGLALQLPALLEGELGEDLYNLGVTIGTIYQMFDDIMDFA-GMEKIGKDGFLDLKNGVASFPLVTAMEKFPEARQ----MFENRDWSGLMSFMREK----GILKECEETLKVLVKNVIIENSWLRD------------------

General information: TITO was launched using: RESULT: Template: 1V4I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -94283 for 2002 contacts (-47.1/contact) + 2D Compatibility (PS) -27106 + (NN) -15836 + (LL) 3800 1D Compatibility (HY) -20400 + (ID) 4050 Total energy: -157875.0 ( -78.86 by residue) QMean score : 0.427

(partial model without unconserved sides chains): PDB file : Tito_1V4I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1V4I-query.scw PDB file : Tito_Scwrl_1V4I.pdb: