Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEWQDLAQLPVSIFKDYVTDAQDAEKPFIWTEVFLREINRSNQEIILHIWPMTKTVILGMLDRELPHLELAKKEIISRGYEPVVRNFGGLAVVADEGIL-NFSLIIPDVFERKLSISDGYLIMVDFIRSIFSDFYQPIEHFEVETSYCPGKFDLSINGKKFAGLAQRRIKNGIAVSIYLSVCGDQKERSRMISDFYKIGLGDTGSPIAYPNVDPEIMANLSDLLDCPMTVEDVIDRMLISLKQ-VGFNDRLLMIRPDLVAEFDRFQAKSMANKGTVSRDE 2QHS Chain:A ((21-230)) --------MEFLVEDLG---LVPYGEAWAYQKRVHREVVAGNRPPTLLLLEHPRVITLGRKATGE-NLLFPESWYRENGFELYWVERGGDVTYHGPGQLVGYPIFPVGR-----EVRRFLRQIEEAIVRVAAGYGISAY-------PTPGYAGVWVGEDKLCAIGVAVKEGVSFHGFALNVNTDLNDFTVIV-----PCGL--------K---GKGVTSLEKLLGRKVPMEEAKARVVAAFAEVFGLRPV------------------------------

General information: TITO was launched using: RESULT: Template: 2QHS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -156193 for 1684 contacts (-92.8/contact) + 2D Compatibility (PS) -22309 + (NN) -8341 + (LL) 4812 1D Compatibility (HY) -3200 + (ID) 1300 Total energy: -186531.0 ( -110.77 by residue) QMean score : 0.349

(partial model without unconserved sides chains): PDB file : Tito_2QHS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QHS-query.scw PDB file : Tito_Scwrl_2QHS.pdb: