Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTNTVTPKETAGSFINKVLGGTATAIVVALIPNAILATFLKPFLSYGLAAEFLHIVQVFQFFTPIMAGFLIGQQFKFTPMQQLAVGGAAYIGSGAWAYTEVIQKGVATGSFQLRGIGDLINMMLTAALAVLAVKWFGNKFGSLTIILLPIIIGTGVGYLGWKLLPYVSYVTTLIGQGINSFTTLQPIAMSILIAMAFS----------MLIVSPISTVAIGLAIGLNGMSASAAS-------MGVASTTAVLVWATMKANKSGVPI--AIALGAMKMMMPNFLKHPVMAIPMLMTATVSSLTVPLFKLVGTPASSGFGLVGAVG-PIASFEAGASMLIVILSWLVIPFAVGFVSHKICKDILKLYKDDIFVFEGQN 4K0E Chain:A ((864-1018)) -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PMVLALMFVLLFGEFKNLRQPALILMAVPLATLGGLVALHLRGMTLNVSSAVGFIALFGVAVLNAIIMIANL-------SLKEAVVRGAGERMRP-----------VLMTATVAALGL-------IPAALAHGLGSDVQRPLATVVVGGLITATALTLVLLPALYYLIETR--------------------

General information: TITO was launched using: RESULT: Template: 4K0E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -100017 for 855 contacts (-117.0/contact) + 2D Compatibility (PS) -13250 + (NN) -4842 + (LL) 17384 1D Compatibility (HY) -12800 + (ID) 1850 Total energy: -115375.0 ( -134.94 by residue) QMean score : 0.111

(partial model without unconserved sides chains): PDB file : Tito_4K0E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4K0E-query.scw PDB file : Tito_Scwrl_4K0E.pdb: