Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVK-VLVVKANVGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVM--ELEETHWDWTMNINAKALLFCAQEAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAVSGGAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMIRGQTIIVDGGRSLLV 2PH3 Chain:A ((2-241)) ----RKALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANLLEAEAATALVHQAAEVLGGLDTLVNNA--GITRDTLLVRMKDEDWEAVLEANLSAVFRTTREAVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNAVAPGFIETEMTERLP--QEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITGQTLCVDGG-----

General information: TITO was launched using: RESULT: Template: 2PH3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1323 -145583 -110.04 -614.27 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -110.04 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.588

(partial model without unconserved sides chains): PDB file : Tito_2PH3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2PH3-query.scw PDB file : Tito_Scwrl_2PH3.pdb: