Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MERHYYTYLIKEEFANHYFGRESVMFELFQD----YHWTS--LEKQQYEMTEKQIQYITQPIPILHMHQRLKMNLNKTDYRQLDYIYRIALPKAKGHATFMMKEHMIEIVASGDYEAETIFFEVLRKVSPCFLAMDFNSKRYGWLNPVKERNFV 1HL6 Chain:B ((4-146)) -EDFYLRYYVGHKGK---FGHEFLEFEFRPDGKLRYANNSNTMIRKEAFVHQSVMEELKRIIIDSEIMQEDDLPWPPPDR---VGRQELEIVIGDEHISFTTSKTLVDVNRSKDPEGLRCFYYLVQDLKCLVFSLIGLHFK---IKP-------

General information: TITO was launched using: RESULT: Template: 1HL6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 534 -2389 -4.47 -18.24 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain B : 0.67 3D Compatibility (PKB) : -4.47 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.191

(partial model without unconserved sides chains): PDB file : Tito_1HL6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1HL6-query.scw PDB file : Tito_Scwrl_1HL6.pdb: