Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVIKGLTAGLIFLFLCACGGQQIKDPLNYEVEPFTFQNQDGKNVSLESLKGEVWLADFIFTNCETICPPMTAHMTDLQKKLKAE-NIDVRIISFSVDPENDKPKQLKKFAANYPLSFDNWDFLTGYSQSEIEEFALKSFKAIVKKPEGEDQVI-HQSSFYLVGPDGKVL----KDYNGVENTPYDDIISDVKSASTLK 2B7J Chain:A ((23-180)) ---------------------------------PFHLEDMYGNEFTEKNLLGKFSIIYFGFSNCPDICPDELDKLGLWLNTLSSKYGITLQPLFITCDPARDSPAVLKEYLSDFHPSILG---LTG-TFDEVKN-ACKKYRVY----------VDHSIFFYLMDPEGQFVDALGRNYD--EKTGVDKIVEHVKS-----

General information: TITO was launched using: RESULT: Template: 2B7J.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 644 -23179 -35.99 -167.96 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -35.99 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.573

(partial model without unconserved sides chains): PDB file : Tito_2B7J.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2B7J-query.scw PDB file : Tito_Scwrl_2B7J.pdb: