Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MLKKVIGILVIIAIISVGFFQKEAWLDAIKAGGMFSVLF-----SMLLIAADVFFPIVPFAL-----IAALNGAVFGTANGIWITLTGSM-LGTILLFFLARYSFRDWARKKVQAYPAIQSYEASFNKNAFTAVLLGRLIPVIPSLVMNVICGLSQV--RWHVFFFASLIGKIPNIVVVTIAGANFTSNKLLSISIYGTYILIIMLVIYKKFPHLLKVPKK 1AER Chain:A ((1-211)) AFLGD--GGDVSFSTRGTQNWTVERLLQAHRQLEERGYVFVGYHGTFLEAAQSIVFGGVRAAIWRGFYIAGDPALAYGYAQDQEPDARGRIRNGALLRVYVPRSSLPGFYRTSLTL--------AAPEAAGEVERLIGHPLP----LRLDAITGPEEEGGRLETILGWPLAERTVVIPSAIPTDPRNVGGDLDPSSIPDKEQAISALPDYASQP---GKPPR

General information: TITO was launched using: RESULT: Template: 1AER.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 963 -41372 -42.96 -216.61 target 2D structure prediction score : 0.32 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -42.96 2D Compatibility (Sec. Struct. Predict.) : 0.32 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.176

(partial model without unconserved sides chains): PDB file : Tito_1AER.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1AER-query.scw PDB file : Tito_Scwrl_1AER.pdb: