Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MELYECIQDIFGGLKNPSVKDLATSLKQIPNAAKLSQPYIKEPDQYAYGRNAIYRNN-ELEIIVINIPPNKETTVHDHGQSIGCAMVLEGKLLNSIY----RSTGEHAELSNSYFVHEGECLISTKGL-IHKMSNPT-SERMVSLHVYSPPLEDMTVFEEQKEVLENS 2GH2 Chain:A ((54-170)) -------------------------------------------DQYRYTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKLLQGNLKETLFDWPDKKSNEMIKKSERT-LRENQCAYINDSIGLHRVENVSHTEPAVSLHLYSPPFDTCHAFDQR-------

General information: TITO was launched using: RESULT: Template: 2GH2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 478 6796 14.22 61.78 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : 14.22 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.399

(partial model without unconserved sides chains): PDB file : Tito_2GH2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2GH2-query.scw PDB file : Tito_Scwrl_2GH2.pdb: