Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKVHQSACPLNCWDSCGFLVTVDDGKVTKV---DGDPN-HPITEGKICGRGRMLETKTNSPDRLRYPMKKQ---------------NGEFVRISWEQALDEIADKLREIKETSETTAVLH-SHDYANNGLLK---ALDQRFFNGYGGVTEIVGSICWGSGIEAQSWDFGRSYGHGPLDIY-----------NSKHVVVWGRNVSRTNM--------HLYHHLQQVKKKGATITVIDPIFNPTAKL--ADRYISVKPGMDGWLAAAVLKVLIEMGRTDETFISEHSVGFDDVKELL--------KTVSLEEFIVKTETSMEELEYLAGLYADGPVSTFMGLGMQRYKNGGGTIRWIDALVAASGNVGIKGGGANFGN---------------VQIGESFAKTKLTLPELKTTSRSFSMMTQAEEVL------------TAADPAIEMIIVTCGNPLTQVPNTNKVRQAFEKVPMTVAIDSIMTDTAELCDYVLPTATVFEEEDIYYSSMYHHY-VQYGKKLVEPQGEAKSDSWIWSELAKRLGFGELFEYSTQEFLEMGLSSLEAEDVTLERLKEKGHLPLPVKQVPW----------DDYQFL---------------TPSGKFEFTSSLAEQKGFSGSLQLNVPEESVFHNEELAGKYPYTLLSIHPQRSNHSQHVPFIEK-----LQHVQVDISPDIAAGQDLQDGDEVVIFNDRGSMKGKVKVMKQAHAKTINIDEGMWAAFGGSVNALTNDTNSDNGMGSTLFDCLVGLKKA 1DMS Chain:A ((17-718)) ------------------FTATVENGRATAFTPWEKDPHPTPMLEGVL--------DSIYSPTRIKYPMVRREFLEKGVNADRSTRGNGDFVRVSWDQALDLVAAEVKRVEETYGPQGVFGGSYGWKSPGRLHNCTTLLRRMLTLAGGYVNGAGDYSTGAA------QVIMPHVVGTLEVYEQQTAWPVLAENTEVMVFWAADPIKTSQIGWVIPEHGAYPGLEALKAKGTKVIVIDPVRTKTVEFFGAD-HVTPKPQTDVAIMLGMAHTLVAEDLYDKDFIANYTSGFDKFLPYLMGETDSTPKTAEWASDI--SGVPAETIKELARLFKSKRTMLAAGWSMQRMHHGEQAHWMLVTLASMLGQIGLPGGGFGLSYHYSGGGTPSSSGPALSGITDG--------------GASVIPVARVVDMLENPGAEFDFNGTRSKFPDVKMAYWVGGNPFVHHQDRNRMVKAWEKLETFIVHDFQWTPTARHADIVLPATTSYERNDIETIGDYSNTGILAMKKIVEPLYEARSDYDIFAAVAERLGKGKEF---TEGKDEMGWIKSFYDDAA--KQGKAGGVEMPAFDAFWAEGIVEFPVTDGADFVRYASFREDPLLNPLGTPTGLIEIYSKNIEKMGYDDCPAHPTWMEPLERLDGPGAKYPLHIAASHPFNRLHSQLNGTVLREGYAVQGHEPCLMHPDDAAARGIADGDVVRVHNDRGQILTGVKVTDAVMKGVIQIYEGGW----------------------------------

General information: TITO was launched using: RESULT: Template: 1DMS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3304 46399 14.04 80.14 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : 14.04 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.468

(partial model without unconserved sides chains): PDB file : Tito_1DMS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DMS-query.scw PDB file : Tito_Scwrl_1DMS.pdb: