Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTRYDSLLQALGNTPLVGLQRLSPRWDDGRDGPHVRLWAKLEDRNPTGSIKDRPAVRMIEQAEADGLLRPGATILEPTSGNTGISLAMAARLKGYRLICVMPENTSVERRQLLELYGAQIIFSAAEGGSNTAVATAKELAATNPSWVMLYQYGNPANTDSHYCGTGPELLADLP-EITHFVAGLGTTGTLMGTGRFLREHVANVKIVAAEPRYG-------EGVYALRNMDEGFVPELYDPEILTARYSVGAVDAVRRTRELVHTEGIFAGISTGAVLHAALGVGAGALAAGERADIALVVADAGWKYLSTGAYAGSLDDAETALEGQLWA 2Q3D Chain:A ((4-309)) MSIAEDITQLIGRTPLVRLRRVT-------DGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKL--IVVVLPDFGERYLSTPLFA----------------

General information: TITO was launched using: RESULT: Template: 2Q3D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -118757 for 2785 contacts (-42.6/contact) + 2D Compatibility (PS) -32537 + (NN) -8578 + (LL) 932 1D Compatibility (HY) -21200 + (ID) 6100 Total energy: -186240.0 ( -66.87 by residue) QMean score : 0.491

(partial model without unconserved sides chains): PDB file : Tito_2Q3D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Q3D-query.scw PDB file : Tito_Scwrl_2Q3D.pdb: