Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKLTKGLGILLASSLVLGLAACGGGSDDKALSTEKITIGTTAGPHQQIAEEVQKLAKKDGLEIKIKTFDDYNTPNTALNDGDLDANNYQTIPFLEQQKKDKGYKLDVAFKTVAFPMGIYSNDIKDLKNLKKGDKIAVPNDPSNEYRGLKLFEDAGVIKLKDGVEEKATKKDIAENPLDLEIVELEASQIPAQLDEVAAAAINTNFAMGAGLSINKDAIYHEPTKDNPYPNVFVVRSANKDDEVVKTLEKYYHSDEVKAFIEKEF-NGSVVPAF 1XS5 Chain:A ((3-240)) ----------------------------------ETVGVGVLSEPHARLLEIAKEEVKKQHIELRIVEFTNYVALNEAVMRGDILMNFFQHVPHMQQFNQEHNGDLVSVGNVHVEPLALYSRTYRHVSDFPAGAVIAIPNDSSNEARALRLLEAAGFIRMRAGSGLFATVEDVQQNVRNVVLQEVESALLPRVFDQVDGAVINGNYAIMAGLSARRDGLAVEPDA-SAYANVLVVKRGNEADARVQAVLRALCGGRVRTYLKERYKGGEVAPA-

General information: TITO was launched using: RESULT: Template: 1XS5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -57939 for 2010 contacts (-28.8/contact) + 2D Compatibility (PS) -25518 + (NN) -11900 + (LL) 1764 1D Compatibility (HY) -14400 + (ID) 3700 Total energy: -111693.0 ( -55.57 by residue) QMean score : 0.575

(partial model without unconserved sides chains): PDB file : Tito_1XS5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XS5-query.scw PDB file : Tito_Scwrl_1XS5.pdb: