Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKFDSQKIITPIMKFVNMRGIIALKDGMLAILPLTVVGSLFLILGQLPFKGLNQAIANVFGPEWTEPFMQVYSGTFAIMGLISCFAIAYAYAKNSSVEPLPAGVLSLSSFFIL---MKSSYIPVKGEAIADAISKVWFGGQGIIGAIIIGLVVGAIYTWFIQHHIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYLIAKVTTGGTFIEMIYDIIQVPLQGLTGSLYGAIGIAFFISFLWWFGVH-----GQSVVNGIVTALLLSNLDANKSLLAANRLTLDNGAHIVTQQFLDSFLILSGSGITFGLVIAMLFAAKSKQYKALGKVAAFPAIFNVNEPIVFGFPIVMNPVMFLPFILVPVLAALIVYGAIAVGFMQPFSGVTLPWSTPAIISGFMVGGWQGALVQIVILAISTAVYFPFFKIQDNITYKNECEMERG 1W5C Chain:D ((1-350)) MTIAIGRA--------------------------------------------PAERGWFDILDDWLKRDRFVFVGWSGIL-LFPCAYLALGGWLTGTTFVTSWYTHGLASSYLEGCNFLTVAVSTPANSMGHSLLLLW--GPEAQGDFTRWCQLGGLWTFIALHGAFGLIGFMLRQFEIARLVGVRPYNAIAFSAPIAVFVSVF-------------LIYPLGQSSWFFAPSFGVAAIFRFLLFFQGFHNWTLNPFHMMGVAGVLGGALLCAIHGATVENTLFQDGEGASTFRAFN-----PTQAEETYSMVTANRFWSQI-------------------------FGIAFSNKRWLHFFMLFVPVTGLWMSAIGVVGL-ALNLRSYDFISQEIRAAEDPEFETFYTKNLLLNEGIRAWMAPQDQPHENFVFPEEVLPRGN

General information: TITO was launched using: RESULT: Template: 1W5C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -206308 for 2310 contacts (-89.3/contact) + 2D Compatibility (PS) -35300 + (NN) -5236 + (LL) 6828 1D Compatibility (HY) -7200 + (ID) 2600 Total energy: -249816.0 ( -108.15 by residue) QMean score : 0.087

(partial model without unconserved sides chains): PDB file : Tito_1W5C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1W5C-query.scw PDB file : Tito_Scwrl_1W5C.pdb: