Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDITFNTGLMGSGKSKKLID-DYLIDPK-EKVALSVSLTEDTFSRG---KIESRDGRSLRSINLNRDQFKQNISLLEIIIFMTNTQTIYIDESQFLPKETVEKFVSLSESYHVPIHFYGLDLTFTGELFDSSSHLLTILPSENINRISRGCEASKCSKI-AQYNARIVDGKVSRSGETFVEEKSY-YLALCSDHYYNDEKII 2ORW Chain:A ((3-181)) GKLTVITGPMYSGKTTELLSFVEIYKLGKKKVAVFK---PK-----HSTMIVS----GVEAHVIER-PE----EMRKYI--EEDTRGVFIDEVQFFNPSLFEVVKDLLD-RGIDVFCAGLDLTHKQNPFETTALLLS--LADTVIKKKAVCHR--CGEYNATLTLKVAGG-----EEEIDVGGQEKYIAVCRDCYNTLK---

General information: TITO was launched using: RESULT: Template: 2ORW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 840 -92696 -110.35 -568.69 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -110.35 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.300

(partial model without unconserved sides chains): PDB file : Tito_2ORW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ORW-query.scw PDB file : Tito_Scwrl_2ORW.pdb: