Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSIYHMKVRTITGKDMTLQPFAGKVLMIVNTASKCGFTSQLKQLQELYDTYQQEGLEILGFPCNQFMNQEPGEEADI---QEFCETNYGV--TFPMFSKVDVNGKNAHPLFVYLTE---HAKGMLGT-----------KAIKWNFTKFIVDRNGEIVGRYSPNTNPKELEDDIVKLLEQ 2I3Y Chain:A ((49-212)) ---------------VSFKQYVGKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLKYVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIRWNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQ

General information: TITO was launched using: RESULT: Template: 2I3Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 644 -7276 -11.30 -50.18 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -11.30 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.517

(partial model without unconserved sides chains): PDB file : Tito_2I3Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I3Y-query.scw PDB file : Tito_Scwrl_2I3Y.pdb: