Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDLKNGSLVTEFILLGFFGRWELQIFFFVTFSLIYGATVMGNILIMVTVTCRSTLHSPLYFLLGNLSFLDMCLSTATTPKMIIDLLTDHKTISVWGCVTQMFFMHFFGGAEMTLLIIMAFDRYVAICKPL-HYRTIMSHKLLKGFAILSWIIGFLHSISQIV-LTMNLP-----FCG------HNVINNIFCDLPLVIKLACIETYTLELFVIA--DSGLLSFTCFILLLVSYIVILVSVPKKSSHGLSKALSTLSAHIIVVTLFFGPCIFIYV----WPFSSLASN-----KTLAVFYTVITPLLNPSIYTLRNKKMQEAIRKLRFQYVSSAQNF 2HPY Chain:A ((58-316)) -----------------------------------------NFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIM-GVA-FTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNN--------------ESFVIYMFVVHFIIPLIVIFFCYGQLV--FTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGDD

General information: TITO was launched using: RESULT: Template: 2HPY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -212528 for 1706 contacts (-124.6/contact) + 2D Compatibility (PS) -23110 + (NN) 3959 + (LL) 5552 1D Compatibility (HY) 1600 + (ID) 700 Total energy: -225227.0 ( -132.02 by residue) QMean score : 0.148

(partial model without unconserved sides chains): PDB file : Tito_2HPY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2HPY-query.scw PDB file : Tito_Scwrl_2HPY.pdb: