Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLLTDRNTSGTTFTLLGFSDYPELQVPLFLVFLAIYNVTVLGNIGLIVIIKINPKLHTPMYFFLSQLSFVDFCYSSIIAPKMLVNLVVKDRTISFLG---CVVQFFFFCTFVVTESFLLAVMAYDRFVAICNPLLYTVNMSQKLCVLLVVGSYAWGVSCSLELTCSALKLCFHGFNTINHFFCEFSSLLSLSCSDTYINQWLLFFLATFNEISTLLIVLTSYAFIVVTILKMRSVSGRRKAFSTCASHLTAITIFHGTILFLYCVPNSKNSRHTVKVASVFYTVVIPMLNPLIYSLRNKDVKDTVTEILDTKVFSY 4S0V Chain:A ((58-187)) ----------------------EYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLP---ATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHP----STAKRARNSIVII----WIVSCIIMIPQAIVMECSTVFKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQGIDCSFWNESYLTGSRDERKKSLLSKFGMDEGVTFMFIGRFDRGQKGVDVLLKAIEILSSKKEFQEMRFIIIGKGDPELEGWARSLEEK

General information: TITO was launched using: RESULT: Template: 4S0V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -99913 for 775 contacts (-128.9/contact) + 2D Compatibility (PS) -12349 + (NN) -4673 + (LL) 1836 1D Compatibility (HY) -12000 + (ID) 1650 Total energy: -128749.0 ( -166.13 by residue) QMean score : 0.172

(partial model without unconserved sides chains): PDB file : Tito_4S0V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4S0V-query.scw PDB file : Tito_Scwrl_4S0V.pdb: