Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIG------------YLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTL--AMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRW-----NNRFSMAMLE 4HLU Chain:A ((22-257)) --------------KKALENVSLVINEGECLLVAGNTGSGKSTLLQIVAGLIEPTSGDVLYDGER--KKGYE---IRRNIGIAFQYPEDQFF-AERVFDEV---AFAVKNFYPDRDP------------VPLVKKAMEFVGLDFDSFKDRVPFFLSGGEKRRVAIASVIVHEPDILILDEPLVGLDREGKTDLLRIV----EKWKTLGKTVILISHDIETVINHVDRVVVLEKGKKVFDGTRMEFLEKYD-PRFFTSKMLVMRRLVLKGEDPFSMS---

General information: TITO was launched using: RESULT: Template: 4HLU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -125506 for 1654 contacts (-75.9/contact) + 2D Compatibility (PS) -23064 + (NN) -4748 + (LL) 3360 1D Compatibility (HY) -18800 + (ID) 4000 Total energy: -172758.0 ( -104.45 by residue) QMean score : 0.428

(partial model without unconserved sides chains): PDB file : Tito_4HLU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HLU-query.scw PDB file : Tito_Scwrl_4HLU.pdb: