Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEWQDLAQLPVSIFKDYVTDAQDAEKPFIWTEVFLREINRSNQEIILHIWPMTKTVILGMLDRELPHLELAKKEIISRGYEPVVRNFGGLAVVADEGILNFSLIIPDVFERKLSISDGYLIMVDFIRSIFSDFYQPIEHFEVETSYCPGKFDLSING---KKFAGLAQRRIKNGIAVSIYLSVCGDQKERSRMISDFYKIGLGDTGSPIAYPNVDPEIMANLSDLLDCPMTVEDVIDRMLISLKQ-VGFNDRLLMIRPDLVAEFDRFQAKSMANKGTVSRDE 1W66 Chain:A ((7-218)) ---IRSKLSAIDVRQLG---TVDYRTAWQLQRELADARVAG-GADTLLLLEHPAVYTAGRRTET--H-E-----RPIDGTPVVDTDRGGKITWHGPGQLVGYPIIGLAE--PLDVVNYVRRLEESLIQVCADLGLHAG-------RVDGRSGVWLPGRPARKVAAIGVRVSRATTLHGFALNCDCDLAAFTAIV-----PCGI--------S---DAAVTSLSAELGRTVTVDEVRATVAAAVCAALDGVLP------------------------------

General information: TITO was launched using: RESULT: Template: 1W66.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -162388 for 1704 contacts (-95.3/contact) + 2D Compatibility (PS) -21941 + (NN) -4319 + (LL) 4780 1D Compatibility (HY) 3200 + (ID) 1400 Total energy: -182068.0 ( -106.85 by residue) QMean score : 0.370

(partial model without unconserved sides chains): PDB file : Tito_1W66.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1W66-query.scw PDB file : Tito_Scwrl_1W66.pdb: