Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLDKAVMRLSGIHKLLGLLAGLDVLQAIFIIGQAYYLSLSITGLWEGQKLSSQTVYILLFMVSYLGRHVIDYIKNRKLDDFSTAQSSLLRRQLLDKLFDLGPKVVQEQGTGNVVTMALDGVSLVENYLRLVLNKMINMSIIPWIILAYIFYLDIESGAILLIVFPLIIIFMIILGYAAQAKADKQYESYQVLSNHFLDSLRGIDTLKYFGLSKRYGKSIYQTSESFRKATMSTLKIGILSTFALDFFTTLSIAIVAVFLGLRLLNEQIYLLPALTILILSPEYFLPVRDFSSDY-HATLDGKNAFQAIQKV-----LNKTGIKGEQLVIDDWSKESHLDLENIAIAYDQKR---VVEDVTLRFRGHQKVALVGVSGSGKSSLINLLSGFLGPDKGSLKVDGREVVNLDQEDWHKQMIYIPQTPYVFEMSLRDNITFYTPNA---SDEEVIRAIHMVGLDSLLSELPDGLETRIGNGARPLSGGQAQRIALARAFLDQNRRIMVFDEPTAHLDIETELELKEKMLPLMSDRLVIFATHRLHWLNQMDVIVVMEKGRVVEVGSYQELLAKKGYLYQLKHAMGGNNV 4M2S Chain:A ((987-1271)) ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSSFAPDYAKATVSASHIIRIIEKTPEIDSYSTQGLKPNML-------EGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIA-YGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQP-HILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSVQA----

General information: TITO was launched using: RESULT: Template: 4M2S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -146976 for 1993 contacts (-73.7/contact) + 2D Compatibility (PS) -29875 + (NN) -11555 + (LL) 25984 1D Compatibility (HY) -24400 + (ID) 4800 Total energy: -191622.0 ( -96.15 by residue) QMean score : 0.465

(partial model without unconserved sides chains): PDB file : Tito_4M2S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4M2S-query.scw PDB file : Tito_Scwrl_4M2S.pdb: