Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MDLLLALLPALFWGSIVLFNVKLGGGPYSQTLGTTIGALIVSIVIYFFVQPVLSLRIFIVGIVSGLFWSLGQANQLKSIQLMGVSKTMPISTGMQLVSTSLFGVIVFREWSTPIAITLGVLALIFIIVGIILTSLEDKNDKKEGEPSNLKKGILILLVSTLGYLVYVVVARLFNVSGWSALLPQAIGMVVGGLVLTYRHKPFNKYAIRNILPGLIWAGGNMF-LFISQPRVGVATSFSLSQMGIVISTLGGIFILREKKTKRQLIAIAIGIILIIAAAVFLGIAKTNS 4O6Y Chain:A ((10-219)) PIFMVVRVLGFIIAALVLTWTVHYRGGLALSSD---------NKDHIFNVHPVMMVIGLI----------------LFNGEAMLAYKSVQGT----------------KNLKKLVHLTLQLTAFILSLIGVWAALKFHIDKGIENFYS---------LHSWLGLACLFLFAFQWAAGFVTYWYPGG-----------------SRNSRASLMPWHVFLGISIYALALVTATTGILEKVTFLQVNQVITRYS---------TEAMLVNTMGVLILILGGFVILGVVT---

General information: TITO was launched using: RESULT: Template: 4O6Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 795 -159417 -200.52 -766.43 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -200.52 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.232

(partial model without unconserved sides chains): PDB file : Tito_4O6Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4O6Y-query.scw PDB file : Tito_Scwrl_4O6Y.pdb: