Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLIEHYVALVKTGCAEYGQMNEMTLTEIADCLFCTERNAKLILHKLENSNWIIRESGAGRGRKSKIAFLRRPEELLLQTAKEYTMSGKLKKAKELLQQYQSAFPGLQNEYNMWLSEVFGFVTETGENGAKDVLRLFITPESVSSLDPCQIFLRSEGHFVKQIFDTLFTFDSDMQEPKPHLVHGWE--EVGKKQWRFFLRKGVLFHNGQP------LTSRDVAFTFQRFLELADNPYKWLLHG-------------VKQVLEKGPYCVELILDKPNALLPYALCDERLSILPAEQGGG-------------KNGTGPFQMNQ-QHSGMLVLEANERYFKGRPYLDRVEFVFSEQAG-EMNGFTIQEKQTCPEQQTVFDER---------------HVQYLSLNLKKKGPLQHRSFRKALRLLISSERLVREAGGHRRIPVTSFLHPS---------PFEWEGVSPSELLKKSGYE-GETIVLYTFS-----ETDHREDAEWIQNICAQHGIRLTLQFCDAAD-LRRPEIVQMADIIHDSATFYQDSEFGFLHLLLSENSFLYQHLSEKLTQICSGMTERMFSMPDRCSRINILRDIDRQMIQELNAIPLYQNVLQVTSSKNVKGLVLDEEGWIDLYSVWLSK 1DPP Chain:A ((32-497)) ------------------------------------------------------------------------------------------------------------------------------------------------------------------LYNRLVEFKIGTTEVIPGLAEKWEVSEDGK-TYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDR-QKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKK-PLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLG-----------

General information: TITO was launched using: RESULT: Template: 1DPP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1955 -126188 -64.55 -316.26 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -64.55 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.293

(partial model without unconserved sides chains): PDB file : Tito_1DPP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DPP-query.scw PDB file : Tito_Scwrl_1DPP.pdb: