Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKTMSAITAAAAVTSCFTGFGAASFSAPAKAAAQTNTLSENTNQSAAELVKNLYNTAYKGEMPQQAQGLTINKSTKGDVHAAFGEPERPVGGDNRFDLYHWNMGQPGYGFSYHKDMTISEIRYFGTGVERQLNLGGVTPEVLQKQLGPVNRVLTVPF--TDEIDYVYDTG--RYELHFVIGTDQTADHVNLKAK 4DM5 Chain:A ((27-80)) ----------------------------------------------------------------------------------------------------------------------------------------GMSQQEVLRIGGTPSGTQKRLMKPGSCNSYILNKDGQQQPFYVSFDGSGKVDGS-----

General information: TITO was launched using: RESULT: Template: 4DM5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 169 -10615 -62.81 -212.29 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain A : 0.56 3D Compatibility (PKB) : -62.81 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.56 QMean score : 0.441

(partial model without unconserved sides chains): PDB file : Tito_4DM5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DM5-query.scw PDB file : Tito_Scwrl_4DM5.pdb: