Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRLIKLEQPNCNPCKMVSNYLEQVNIQFET------VDVTQEPEVAARFGVMGVPVTILLSDQGEEVNRSVGFKPNELDELLKELR 2I1U Chain:A ((29-108)) --LVDFWATWCGPCKMVAPVLEEIATERATDLTVAKLDVDTNPETARNFQVVSIPTLILFKD-GQPVKRIVGAKGKA--ALLREL-

General information: TITO was launched using: RESULT: Template: 2I1U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 253 -3418 -13.51 -46.19 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -13.51 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.621

(partial model without unconserved sides chains): PDB file : Tito_2I1U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I1U-query.scw PDB file : Tito_Scwrl_2I1U.pdb: