Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVTKILKAPDGSPSDVERIKKESDYLRGTLKEVMLDRISAGIPDDDNRLMKHHGSYLQDDRDLRNERQKQKLEPAYQFMLRVRMPGGVSTPEQWLVMDDLSQKYG-NGTLKLTTRETFQMHGILKWNMKKTIQTIHSALLDTIAACGDVNRNVMCASNPYQSEIHSEVYEWSKKLSDDLLPRTRAYHEIWLDEERVA---GTPEEEVEPMYGPLYLPRKFKIGIAVPPSNDIDVFSQ--DLGFIAIVEDGKLIGFNVAIGGGMGMTHGDTATYPQLAKVIGFCRPEQMYDVAEKTITIQRDYGNRSVRKNARFKYTVDRLGLENVKEELENRLGW------SLEEAKPYHFDHNGDRYGWVEGIEDKWHFT-LFVEGGRITDYDDYKLMTGLREIAKVH-TGEFRLTANQNLMIANVSSDKKEEI--SALIEQYGLTDGKHYSALRRSSMACVALPTCGLAMAEAERYLPTLLDKIEEIIDENGLRDQEITIRMTGCPNGCARHALGEIGFIG---KAPGKY----NMYLGAAFDG-SRLSKMYRENIGEADILSELRILL----SRYAKEREEGEHFGDFVIRAGIIKATTDGTNFHD 3B0H Chain:A ((131-581)) ----------------------------------------------------------------------------RFMMRLKLPNGVTTSSQTRYLASVIRKYGKDGCADVTTRQNWQIRGVVLPDVPEILKGLDEVGLTSLQSGMDNVRNPV--GNPLAGIDPHEIVD------------TRPYTNL-LSQYVTANFRGNP--------AVTNLPRKWNV--CVIGSHDLYEHPQINDLAYMPATKDGRF-GFNLLVGGFFSPKRCAEAV-----PLDAWVPADDVVPVCKAILEAYRDLGTRGNRQKTRMMWLVDELGVEGFRAEVVKRMPQQKLDRESTEDLVQKQWERR-EYLGVHPQKQEGYSFVGLHIPVGRVQADD----MDELARLADEYGSGELRLTVEQNIIIPNVKNSKIEALLNEPLLKNRFSTDP---PILMKNLVACTGNQFCGKAIIETKARSMKITEEVQLLVSIT----QPVRMHWTGCPNSCAQVQVADIGFMGCLTRKEGKTVEGADVYLGGRIGSDSHLGDVYKKSVPCEDLVPIIVDLLVDNFGAVPR-----------------------------

General information: TITO was launched using: RESULT: Template: 3B0H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2567 68913 26.85 162.91 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : 26.85 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.357

(partial model without unconserved sides chains): PDB file : Tito_3B0H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3B0H-query.scw PDB file : Tito_Scwrl_3B0H.pdb: