Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKILVLAVHPHMETSVVNKAWAEELSKHDNITVRDLYKEYPDEAIDVAKEQQLCEEYDRIVFQFPLYWYSSPPLLKKWQDLVLTYGWAFGSEG----NALHGKELMLAVSTGSEAEKYQAGGANHYSISELLKPFQ-ATSNLIGMKYLPPYVFYGVNYAAAEDISHSAKRLAEYIQQPFV 3OX2 Chain:A ((82-200)) -------------------------------------------ASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDS-RYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEE-----------------

General information: TITO was launched using: RESULT: Template: 3OX2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 436 -22272 -51.08 -195.37 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -51.08 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.440

(partial model without unconserved sides chains): PDB file : Tito_3OX2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OX2-query.scw PDB file : Tito_Scwrl_3OX2.pdb: