Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLDTQQIKEIIPHRYPFLLVDRITEVEEGKRAKGYKNVTANEEFFNGHFPQYPVMPGVLIVEALAQVGAVAMLIK------EENRGRLAFFAGIDNCRFKKQVKPGDQLHLEVEIIRARGTIGRGKGVATVDGEVVCEVELTFALGE 3DOZ Chain:A ((15-157)) ----EHILQILPHRYPMLLVDRITELQANQKIVAYKNITFNEDVFNGHFPNKPIFPGVLIVEGMAQSGGFLAFTSLWGFDPEIAKTKIVYFMTIDKVKFRIPVTPGDRLEYHLEVLKHKGMIWQVGGTAQVDGKVVAEAELKAMIAE

General information: TITO was launched using: RESULT: Template: 3DOZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 653 -47000 -71.98 -343.07 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -71.98 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.538

(partial model without unconserved sides chains): PDB file : Tito_3DOZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DOZ-query.scw PDB file : Tito_Scwrl_3DOZ.pdb: