Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEFVLLGFSDIPNLHWMLFSIFLLMYLMILMCNGIIILLIKI---HPALQTPMYFFLSNFSLLEICYVTIIIPRMLMDIWTQKGNISLFA---CATQMCFFLMLGGTECLL-LTVMAYDRYVAICKPL-QYPLVMNHKV------------CIQLIIASWTITIPVVIGETCQI-FLLPFCGTNTINHFFCDIPPILKLACGNIFVNEITVHVVAVVFITVPFLLIVVSYGKIISNILKLSSARGKA----KAFSTCSSHLIVVILFF------GAGTITYLQPKPHQFQRMGKL---ISLFYTILIPTLNPIIYTLRNKDIMVALRKLLAKLLT 2HPY Chain:A ((38-313)) ---------------WQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLF---MVFGGFTTTLYTSLHGYFVFGPTGCNLE-GFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETN----------------------NESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYI--FTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKN

General information: TITO was launched using: RESULT: Template: 2HPY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -222955 for 1757 contacts (-126.9/contact) + 2D Compatibility (PS) -24306 + (NN) -5548 + (LL) 3056 1D Compatibility (HY) -6400 + (ID) 800 Total energy: -256953.0 ( -146.25 by residue) QMean score : 0.063

(partial model without unconserved sides chains): PDB file : Tito_2HPY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2HPY-query.scw PDB file : Tito_Scwrl_2HPY.pdb: