Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEGKNQTNISEFLLLGFSSWQQQQVLLFALFLCLYLTGLFGNLLILLAIGSDHCLHTPMYFFLANLSLVDLCLPSATVPKMLLNIQTQTQTISYPGCLAQMYFCMMFANMDNFLLT-------VMAYDRYVAICHPLHYSTIMALRLCASLVAAPWVIAILNPLLHTLMMAHLHFCSDNVIHHFFCDINSLLPLSCSDTSLNQLSVLATVGLIFVVPSVCI----LVSYILIVSAVMKVPSAQGKLKAFSTCGSHLALVILFYGAITGVYMSPLSNHSTEKDSAASVIFMVVAPVLNPFIYSLRNNELKGTLKKTLSRPGAVAHACNPSTLGGRGGWIMRSGDRDHPG 2YCZ Chain:A ((9-239)) ------------------QWEAGMSLLMALVVLLIVAG---NVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVP-------FGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMM----HWWRDEDPQALKCYQDP----GCCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIRKIDRA-SKRKRVMLMREHKALKTL--GIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYCRSPDFRKAFKRLLAF------------------

General information: TITO was launched using: RESULT: Template: 2YCZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -152243 for 1401 contacts (-108.7/contact) + 2D Compatibility (PS) -22851 + (NN) -12367 + (LL) 4292 1D Compatibility (HY) -18800 + (ID) 3150 Total energy: -205119.0 ( -146.41 by residue) QMean score : 0.074

(partial model without unconserved sides chains): PDB file : Tito_2YCZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YCZ-query.scw PDB file : Tito_Scwrl_2YCZ.pdb: