Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSQRVSYYEIAPEGMKIMMDMEKY-TK-QSSINRTTRELIKIRVSQMNGCAFCIDMHTSDARKMGETEQRIYCLHAWNECDFYSPEEKAALELSEHITLIPSKRVPDELYHRVRE-HYDEEQYVDLVLIINQINSWNRISIAMGNRAASK 3C1L Chain:A ((35-181)) -PNVLKAYAFDDKKLRAFTDIYNDLMLGESGLSKLDREMIAVAVSSINHCYYCLTAHGAAVRQLSGDPALGEMLVMNFRAADLSPRQTAMLEFAVKLTEEP-AKIVEADRAALRKAGFSDRDIWDIASTAAFFNMSNRVAAAIDMRPND-

General information: TITO was launched using: RESULT: Template: 3C1L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 580 -68926 -118.84 -478.65 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -118.84 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.306

(partial model without unconserved sides chains): PDB file : Tito_3C1L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3C1L-query.scw PDB file : Tito_Scwrl_3C1L.pdb: