Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKSKGVESRKRLLKAAANEFSVRGFHDAKVSEIVKKAGFTQPSFYLYFQSKEAIFAELITDFHSRVRKLTESLLLENGLNTEDVSKRVLLAVETVFQFLDEDKDLTKI--------GFFLNPEAKQMKKDLAMVLKENLEAEQRLGYFHSELDMETVAECLVGMIEHLTESFLLTGIK-DPASLAAEVVNLLIYGMLPKGNDVR 1VI0 Chain:A ((12-196)) ----------QIIDAAVEVIAENGYHQSQVSKIAKQAGVADGTIYLYFKNKEDILISLFKEKMGQFIERMEEDIKEKATAKE----KLALVISKHFSLLAGDHNLAIVTQLELRQSNLELRQKINEILKGYLNILDGILTEGIQSGEIKEGLDVRLARQMIFGTIDETVTTWVMNDQKYDLVALSNSVLELLVSGIHNK-----

General information: TITO was launched using: RESULT: Template: 1VI0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 596 -97619 -163.79 -554.65 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -163.79 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.588

(partial model without unconserved sides chains): PDB file : Tito_1VI0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VI0-query.scw PDB file : Tito_Scwrl_1VI0.pdb: