Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSAGNGTPWDATWNITVQWLAVDIACRTLMFLK---LMATYSAAFLPVVIGLDRQAAVLNPL---GSRSGVRK--LLGAAWGLSFLLAFPQLFLFHTVHCAGPVP---FTQCVTKGSFKAQWQETT----YNLFTFCCLFLLPLTAMAICYSRIVLSVSRPQTRKGSHAPAGEFALPRSFDNCPRVRLRALRLALLILLTFILCWTPYYLLGMWYWFSPTMLTEVPPSLSHILFLLGLLNAPLDPLLYGAFTLGCRRGHQELSIDSSKEGSGRMLQEEIHAFRQLEVQKTVTSRRAGETKGISITSI 2YDV Chain:A ((73-289)) ------------------------ACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWN--NCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQ------------STLQKEVHAAKSLAIIVGL-FALCWLPLHIINCFTFFCPD-CSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAAAENLYFQ----------------------

General information: TITO was launched using: RESULT: Template: 2YDV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -154855 for 1287 contacts (-120.3/contact) + 2D Compatibility (PS) -20285 + (NN) -11543 + (LL) 3500 1D Compatibility (HY) -18400 + (ID) 2650 Total energy: -204233.0 ( -158.69 by residue) QMean score : 0.229

(partial model without unconserved sides chains): PDB file : Tito_2YDV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YDV-query.scw PDB file : Tito_Scwrl_2YDV.pdb: