Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKGS---VPVLIIHIFIVFSFFLVFLIILFC--NLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAVFIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN 4RWD Chain:A ((128-400)) --------------------LYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIF--NLALADALATSTLPFQSAKYLME-TWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRP-----RDGAVV-CMLQFPSPSWYWDTVTKICVFL-FAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALH----LCIALGYANSSLNPVLYAFLDENFKRCFRQLC----------------------------------

General information: TITO was launched using: RESULT: Template: 4RWD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -273829 for 2037 contacts (-134.4/contact) + 2D Compatibility (PS) -27047 + (NN) -6201 + (LL) 4352 1D Compatibility (HY) -23200 + (ID) 3600 Total energy: -329525.0 ( -161.77 by residue) QMean score : 0.264

(partial model without unconserved sides chains): PDB file : Tito_4RWD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4RWD-query.scw PDB file : Tito_Scwrl_4RWD.pdb: