Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKFDRHRRLRSSATMRDMVRENHVRKEDLIYPIFVVEKDDVKKEIKSLPGVYQISLNLLESELKEAYDLGIRAIMFFGVPNSKDDIGTGAYIHDGVIQQATRIAKKMYDDLLIVADTCLCEYTDHGHCGVIDDHTHDVDNDKSLPLLVKTAISQVEAGADIIAPSNMMDGFVAEIRRGLDEAGYYN-IPIMSYGVKYASSFFGPFRDAADSAPSFGDRKTYQMDPANRLEALRELESDLKEGCDMMIVKPALSYLDIVRDVKN-HTNVPVVAYNVSGEYSMTKAAAQNGWIDEERVVMEQMVSMKRAGADMIITYFAKDICRYLDK 1PV8 Chain:A ((30-329)) ---------------------------NLIYPIFVTDVPDDIQPITSLPGVARYGVKRLEEMLRPLVEEGLRCVLIFGVP------------EESPAIEAIHLLRKTFPNLLVACDVCLC----------------AFRAEESRQRLAEVALAYAKAGCQVVAPSD--DGRVEAIKEALMAHGLGNRVSVMSYSAKFASCFYGPFRDAA-------------LPPGARGLALRAVDRDVREGADMLMVKPGMPYLDIVREVKDKHPDLPLAVYHVSGEFAMLWHGAQAGAFDLKAAVLEAMTAFRRAGADIIITYYTPQLLQWLKE

General information: TITO was launched using: RESULT: Template: 1PV8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -190759 for 2110 contacts (-90.4/contact) + 2D Compatibility (PS) -28560 + (NN) -12864 + (LL) 3460 1D Compatibility (HY) -22800 + (ID) 5300 Total energy: -256823.0 ( -121.72 by residue) QMean score : 0.606

(partial model without unconserved sides chains): PDB file : Tito_1PV8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1PV8-query.scw PDB file : Tito_Scwrl_1PV8.pdb: