Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKHLIIVESPAKAKTIKNFLDKN----------YEVV---------ASKGHVRDL-SKFAL-GIKIDETGFTPNY-------------VVDKDH------------KELVKQIIELSKKASITYIATDEDREGEAIGYHVACLIGGKLESYPRIVFHEITQNAILNVLKTPRKIDMFKVNAQQARRLLDRIVGFKLSSLIASKITKG-LSAGRVQSAALKLVIDREKEIRPF-KPLTYFTLDALFEPHLEAQLISYKGNKLKAQELIDEKKAQEIKNELEKESYIISSIIKKSKKSPTPPPFMTSTLQQSASSLLGFSPTKTMSIAQKLYEGVATPQGVMGVITYMRTDSLNIAKEALEEARAKILKDYGKDYLPPKAKVYSSKNKNAQEAHEAIRPTSII--------LEPNALKDYLKPEELKLYTLIYKRFLASQMQDALFESQSVVVACEKGEFKASGRKLLFDGHYKILGNDDKDKLL-----PNLKENDPIKLEKLESNAHVTEPPARYSEASLIKVLESLGIGRPSTYAPTISLLQNRDYIKVEK-KQISALESAFKVIEILEKHFEEIVDSKFSASLEEELDNIAQNKADYQQVLKDFYYPFMDKIEAGKKNIISQKVHEKTGQSCPKCGGELVKKNSRYGEFIACNNYPKCKYIKQTENANDEAKQELCEKCGGEMVQKFSRNGAFLACNNYPECKNTKSLKNTPNAKETIEGVKCPECGGDIALKRSKKGSFYGCNNYPKCNFLSNHKPINKRCEKCHYLMSERIYRKKKAHECIQCKERVFLEEDNG 4DDT Chain:A ((544-1103)) ---LIIVESPTKAETLSRFLGRASSRKERNIIVHEAVTGEGVILFTATRGHVYDLVTKGGIHGVEEENGKFVPVYNSLKRCRDCGYQFTEDRDECPVCSSKNIDDKTETLRALREISLEADEILVATDPDVEGEKISWDVTQYLLPSTRSLRRIEMHEITRYGFKKARESVRFVDFNLVKAQIVRRVQDRWIGFELSGKLQKRFGRSNLSAGRVQSTVLGWIVEREEEYKKSEKDFTLLVLENGVNLEVEGKIADDVVTVVELQE------AEEEKNPL--------------------PPYTTSSALSEISQKLRLGVQEVMDILQDLFEK--------GFITYHRTDSTRISLEGQNVART-YLRKIGKE------DIFMGRSWSTEGAHEAIRPVKPIDARELEEMIEEGLIAD-LTKKHLRVYELIFNRFLASQSAAVKVKKQIVTVDVD-------GKRMGIEQIVEIL-RDGWNLFVPLTVSPRFEHRTYKIKEKKFYKKH-TVPL--FTQASIVEEMKKRGIGRPSTYAKIVEVLFRRGYVYEDKYKRVRPTRFGVMVYSYLKERYEKYVTEETTRRLEEIMDKVERGEEDYQATLRLLYEEIKSLMEE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4DDT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -123971 for 3917 contacts (-31.6/contact) + 2D Compatibility (PS) -52124 + (NN) -4694 + (LL) 11912 1D Compatibility (HY) -32000 + (ID) 8650 Total energy: -209527.0 ( -53.49 by residue) QMean score : 0.342

(partial model without unconserved sides chains): PDB file : Tito_4DDT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DDT-query.scw PDB file : Tito_Scwrl_4DDT.pdb: