Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKND-QIVFEKTKNIAHDINQMQNQQEIIDY-------LFRQDSLTLNQLKHY--YSEPSLPLQ------FLVKV----AVLCMFI-----SMTLASFLFIQAKEVFTNTILSDISPAVFSIF--TVICIFM-----TYTKIIKKGNKNKGKASLNQRSEFYEKNK------LINTIL------------YKKYKMDQQNIQANK------HTASDNEDSMNFSAVLNH-----VLTISKNDKELLGYLDTRDNAMLSQLKAYFSTRPFSLPHYMSLMFCGSI---IVVYATSLFSGQINYIDIPHIFIFLLLIIFLKILIDLIKLLNISRKGQLHTVLHFAQRAEYLRM---RGVIDFILTE-------RYNKKIM--------------- 4ZOX Chain:A ((53-431)) MSNNSLTYFDKHTDSVFAIGHHPNLPLVCTGGGDNLAHLWTSHSQPPKFAGTLTGYGESVISCSFTSEGGFLVTADMSGKVLVHMGQKGGAQWKLASQMQEVEEIVWLKTHPTIARTFAFGATDGSVWCYQINEQDGSLEQLMSGFVHQQD----CSMGEFINTDKGENTLELVTCSLDSTIVAWNCFTGQQLFKITQAEIKGLEAPWISLSLAPETLTKGNSGVVACGSNNGLLAVINCNNGGAILHLSTVIELKPEQDELDASIESISWSSKFSLMAIGLVCGEILLYDTSAWR-------VRHKFV--LEDSVTKLMFDNDDLFASCINGKVYQFNARTGQEKFVCVGHNMGVLDFILLHPVANTGTEQKRKVITAGDEGVSLVFEVPN

General information: TITO was launched using: RESULT: Template: 4ZOX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1478 -222189 -150.33 -766.17 target 2D structure prediction score : 0.20 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -150.33 2D Compatibility (Sec. Struct. Predict.) : 0.20 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.083

(partial model without unconserved sides chains): PDB file : Tito_4ZOX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ZOX-query.scw PDB file : Tito_Scwrl_4ZOX.pdb: