Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRILFIGDVVGSPGRDMVKEYVPKLKTKYKPHFTIINGENAAHGKGLTEKIYHSLIQSGADAITMGNHTWDKKEIFDFIDDVPNLVRPANFPEGTPGKGITYVKANGKELAVINLQGRTFLPPLDDPFLKADELIAEAAKRTPYIFIDFHAEATSEKLALGWYTDGRASAVVGTHTHVQTADNRILPKGTAYITDVGMTGPYDGILGMDRETIIKRFKTNLPVRFTVAEGKTTLSGVVIDIDDQTKKAVKIERILINDDHMFFE 2Z06 Chain:A ((1-251)) MRVLFIGDVMAEPGLRAVGLHLPDIRD--RYDLVIANGENAARGKGLDRRSYRLLREAGVDLVSLGNHAWDHKEVYALLES-EPVVRPLNYPPGTPGKGFWRLEVGGESLLFVQVMGRIFMDPLDDPFRALDRLLE--EEKADYVLVEVHAEATSEKMALAHYLDGRASAVLGTHTHVPTLDATRLPKGTLYQTDVGMTGTYHSIIGGEVETFLARFLTGRPQPFRAAQGKARFHATELVFE--GGRPVAISPYVWEE------

General information: TITO was launched using: RESULT: Template: 2Z06.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1546 -142083 -91.90 -566.07 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -91.90 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.625

(partial model without unconserved sides chains): PDB file : Tito_2Z06.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Z06-query.scw PDB file : Tito_Scwrl_2Z06.pdb: