Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSFNANLDTLYRQVIMDHYKNPRNKGVLNDSI-VVDMNNPTCGDRIRLTMKLDGDIVEDAKFEGEGCSISMASASMMTQAIKGKDIETALSMSKIFSDM-MQGKEYDDSIDLGDIEALQGVSKFPARIKCATLSWKALEKGVAKEEGGN 2QQ4 Chain:J ((4-137)) ------LDELYREILLDHYQSPRNFGVLPQATKQAGGMNPSCGDQVEVMVLLEGDTIADIRFQGQGCAISTASASLMTEAVKGKKVAEALELSRKFQAMVVEGAPPDPT--LGDLLALQGVAKLPARVKCATLAWHALEEAL-------

General information: TITO was launched using: RESULT: Template: 2QQ4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain J - contact count / total energy / energy per contact / energy per residue : 645 21424 33.21 162.30 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain J : 0.85 3D Compatibility (PKB) : 33.21 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.535

(partial model without unconserved sides chains): PDB file : Tito_2QQ4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QQ4-query.scw PDB file : Tito_Scwrl_2QQ4.pdb: