Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGRGNSTEVTEFHLLGFGVQHEFQHVLFIVLLLIYVTSLIGNIGMILLIKTDSRLQTPMYFFPQHLAFVDICY-----TSAITPKMLQSFTEENNLITFRGCVIQFLVYATFATSDCYLLAIMAMDCYVAICKP----LRYPMIMSQT--VYIQLVAGSYIIGSINASVHTGFTFSLSFCKSNKINHFFCDGLPILALSCSNIDINIILDVVFVGFDLMFTELVIIFSYIYIMVTILKMSSTAGRKKSFSTCASHLTAVTIFYGTLSYMYLQPQSNNSQENMKVASIFYGTVIPMLNPLIYSLRNKEGK 4YAY Chain:A ((132-266)) --------------------------------IIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYAS-----VFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAG---LASLPAIIHRNVFFIITVCAFHYETLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLL------

General information: TITO was launched using: RESULT: Template: 4YAY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -75582 for 745 contacts (-101.5/contact) + 2D Compatibility (PS) -12337 + (NN) -1466 + (LL) 3544 1D Compatibility (HY) -17600 + (ID) 1850 Total energy: -105291.0 ( -141.33 by residue) QMean score : 0.108

(partial model without unconserved sides chains): PDB file : Tito_4YAY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YAY-query.scw PDB file : Tito_Scwrl_4YAY.pdb: