Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRKHTAITTFILLGLTEDPQLQVLLFMFLFITYMLSVTGKLTIIALTMLDPHLKTPMYFFLQNLSFLEI-----SFTATCVPRFLYSISTGNKIITYNACVIQLFFADLFGVTEFFLLATMSYDRYVAICKPLHYMAIMSNKVCKTMVICCWMAALMIILPPLSLGFHLEFCDSNVINHFGCDALPILKIPCSDTSLIEQMVVASAVLTFIITLVCVVLSYTYIIRTILKFPSVQQKKKAFSTCSSHIT-----------VVSITYGSCIFIYIKPSAKEEVNINKGVSVLISSISPMLNSFIYTLRNEQVKQAFHDSLKKIAFRLKK 2PED Chain:A ((36-316)) -----------------EPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTT-----LYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAF-TWVMALACAAPPL-VGWS-RYIPEGMQCSCGID----YYTPHEETN-NESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGD

General information: TITO was launched using: RESULT: Template: 2PED.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -209376 for 2029 contacts (-103.2/contact) + 2D Compatibility (PS) -26468 + (NN) -5045 + (LL) 2872 1D Compatibility (HY) 1600 + (ID) 600 Total energy: -237017.0 ( -116.81 by residue) QMean score : 0.134

(partial model without unconserved sides chains): PDB file : Tito_2PED.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2PED-query.scw PDB file : Tito_Scwrl_2PED.pdb: