Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFLSIMAGVIAFVLTVIAIPRFIKFYQLKKIGGQQMHEDVKQHLAKAGTPTMGGTVFLIV--ALLVSLIFSIILSKENSGNLGATFGILSVVLIYGIIGFLDDFLKIFKQINEGLTPKQKMSLQLIAGLIFYFVHVLPSGTSAINIFGFYLEVGYLYAFFVLFWVVGFSNAVNLTDGIDGLASISVVISLITYGIIAYNQTQFDILLIIVIMIGALLGFFVFNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLFIGFVYVFETSSVMLQVAYFKYTKKKTGVGKRIFRMTPFHHHLELGGVSGKGNKWSEWKVDAFLWAIGIFMSAITLAILYL- 4ART Chain:A ((22-270)) --------------------------IDATNDEEKLADIVENEIEKEIRKIENFYYYILRDGKIYPASDYDIEVEKGKRSANDIYAFVETDVT--------RDFDEFLFDIDYGLP-------------------------SISDILKFYLEKA------------GFRIANEVPTPN---------LKYYIHAVVEFPQ----YLAVNIYDIDSLARALRIPQIVEQKL-GNKPRTITADEFNDIERIVAEEQPIL-AGY-----TYDEALRIPYHYYVDHNNSFKDDALKIAHAYLQL-----------FPTPYQVCYEWKARWFNKIDCLKLERLK

General information: TITO was launched using: RESULT: Template: 4ART.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -212604 for 1796 contacts (-118.4/contact) + 2D Compatibility (PS) -25257 + (NN) -7592 + (LL) 9444 1D Compatibility (HY) -7200 + (ID) 1850 Total energy: -245059.0 ( -136.45 by residue) QMean score : 0.109

(partial model without unconserved sides chains): PDB file : Tito_4ART.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ART-query.scw PDB file : Tito_Scwrl_4ART.pdb: