Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLP--RGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE 1GII Chain:A ((4-287)) -----FQKVEKIGEGTYGVVYKARNKLTGEVVALKKI-----------VPSTAIREISLLKELN---HPNIVKLLDVIHT-----ENKLYLVFEHVHQDLKTFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF----------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQ-------

General information: TITO was launched using: RESULT: Template: 1GII.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -189125 for 2055 contacts (-92.0/contact) + 2D Compatibility (PS) -28120 + (NN) -16591 + (LL) 684 1D Compatibility (HY) -31200 + (ID) 6650 Total energy: -271002.0 ( -131.87 by residue) QMean score : 0.478

(partial model without unconserved sides chains): PDB file : Tito_1GII.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GII-query.scw PDB file : Tito_Scwrl_1GII.pdb: