Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEVSLNHPASNTTSTKNNNSAFFYFESCQPPSPALLLLCIAYTVVLIVGLFGNLSLIIIIFKKQRKAQNFTSILIANLSLSDTLVCVMCIHFTIIYTLMDHWIFGDTMCRLTSYVQSVSISVSIFSLVFTAVERYQLIVNP-RGWKPSVTHAYWGITLIWLFSLLLSIPFFLSYHLTDEPFRNLSLPTDLYTHQVACVENWPSKKDRLLFTTSLFLLQYFVPLGFILICYLKIVICLRRRNAKVDKKKENEGRLNENKRINTMLISIVVTFGACWLPRISSMSSLTGIMRC 2I36 Chain:A ((42-267)) ----------------------------------------AYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPH--------EETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAA---QQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGS

General information: TITO was launched using: RESULT: Template: 2I36.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -161953 for 1577 contacts (-102.7/contact) + 2D Compatibility (PS) -22076 + (NN) 1418 + (LL) 2784 1D Compatibility (HY) -26400 + (ID) 2700 Total energy: -208927.0 ( -132.48 by residue) QMean score : 0.224

(partial model without unconserved sides chains): PDB file : Tito_2I36.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I36-query.scw PDB file : Tito_Scwrl_2I36.pdb: