Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPR---ELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQGFN-LKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKG-VSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST 4BKY Chain:A ((12-264)) ---------YELHETIGTGGFAKVKLACHILTGEMVAIKIMDK-----NTL--DLPRIKTEIEALKNLRHQHICQLYHVLETAN-KIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC-A--------------SLAYAAPELIQGK---GSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSIL--LLQQMLQVDPKKRISMKNLLNHPWIMQD

General information: TITO was launched using: RESULT: Template: 4BKY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -142773 for 1753 contacts (-81.4/contact) + 2D Compatibility (PS) -24402 + (NN) -11237 + (LL) 908 1D Compatibility (HY) -26800 + (ID) 4950 Total energy: -209254.0 ( -119.37 by residue) QMean score : 0.391

(partial model without unconserved sides chains): PDB file : Tito_4BKY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4BKY-query.scw PDB file : Tito_Scwrl_4BKY.pdb: