Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence M------DELDIAFFILPLG-------IMLLSIVGTCICKNPY----LMPMLSLVISLVLTFTIFNQSFLGWAVVYSLVSLALSYITLIVVRKRKESGN 1Q38 Chain:A ((1-89)) MRGSNAPQPSHISKYILRWRPKNSVGRWKEATIPGH---LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPGS-------RSHHHHHH

General information: TITO was launched using: RESULT: Template: 1Q38.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 209 -30969 -148.18 -430.13 target 2D structure prediction score : 0.21 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -148.18 2D Compatibility (Sec. Struct. Predict.) : 0.21 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.128

(partial model without unconserved sides chains): PDB file : Tito_1Q38.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q38-query.scw PDB file : Tito_Scwrl_1Q38.pdb: